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Generic Ketotifen is a relatively selective, non-competitive H1-antagonist and mast cell stabilizer. Generic Ketotifen effects several interdependent pathways that mediate asthma and anaphylaxis including calcium fluxes in excitable cells, production and release of mediators of hypersensitivity and inflammation, smooth-muscle contractility, and the density and sensitivity of adrenergic receptors. Decreased chemotaxis and activation of eosinophils has also been demonstrated. In patients with HIV, Generic Ketotifen has been shown to decrease tumor necrosis factor secretion, which has lead to study of Generic Ketotifen in wasting syndromes associated with HIV.

Active Ingredients: ketotifen fumarate
Inactive Ingredients: glycerol, sodium hydroxide/hydrochloric acid (to adjust pH) and purified water.

Generic Ketotifen is used to minimize the frequency and severity of asthma attacks. This medication may allow for a reduction in the use of other asthma medications. Generic Ketotifen is not effective in treating an active asthma attack (acute attack).