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Generic Digiter
Generic "Digiter" binds to a site on the extracellular aspect of the a-subunit of the Na+/K+ ATPase pump in the membranes of heart cells (myocytes).
CLASS and MECHANISM of Action Generic "Digiter" binds to a site on the extracellular aspect of the a-subunit of the Na+/K+ ATPase pump in the membranes of heart cells (myocytes). This causes an increase in the level of sodium ions in the myocytes, which then leads to a rise in the level of calcium ions. The proposed mechanism is the following: inhibition of the Na+/K+ pump leads to increased Na+ levels, which in turn slows down the extrusion of Ca2+ via the Na+/Ca2+ exchange pump. Increased amounts of Ca2+ are then stored in the sarcoplasmic reticulum and released by each action potential, which is unchanged by Generic "Digiter". This is a different mechanism from that of catecholamines. Generic "Digiter" also increases vagal activity via its central action on the central nervous system, thus decreasing the conduction of electrical impulses through the AV node. This is important for its clinical use in different arrhythmias.
Active Ingredients: Digoxin Inactive Ingredients: Corn starch, croscarmellose sodium, microcrystalline cellulose, pregela-tinized starch, lactose monohydrate and anhydrous lactose, silicon dioxide. What is Generic "Digiter" PRESCRIBED For? Generic "Digiter" used to treat heart failure and abnormal heart rhythms (arrhythmias). It helps the heart work better and it helps control your heart rate. This medication is sometimes prescribed for other uses.
Ask your doctor or pharmacist for more information. |
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